The Restylane family of products should not be used by people who:
- Are pregnant, breastfeeding, or under 22 years of age
- Have recently used drugs that thin the blood or prevent clotting
- Have had previous bad allergies, particularly to microorganisms known as gram-positive bacteria
- Have serious allergies to drugs that have previously required in-hospital treatment
- Have bleeding disorders
- Have a known allergy to lidocaine, if using Restylane Silk, Restylane Lyft, Restylane, Restylane Refyne or Restylane Defyne